Antimicrobial Abietane-Type Diterpenoids from Plectranthus punctatus
نویسندگان
چکیده
منابع مشابه
Antimicrobial Abietane-Type Diterpenoids from Plectranthus punctatus.
Four new para-benzoquinone containing abietane-type diterpenoids (1-4) along with thirteen known diterpenoids (5-17) were isolated from the roots of Plectranthus punctatus. The structures of the compounds were established by detailed spectroscopic analyses and comparison with literature data. The compounds were tested for their antibacterial and cytotoxic activity and showed significant inhibit...
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Background and objectives: The genus Salvia is one of the largest genera in the family Lamiaceae and represents approximately 1000 species displaying a remarkable diversity.Salvia tebesana Bunge(Lamiaceae) is an endemic medicinal species that grows wild in center of Iran which is locally named “Maryamgoli Tabasi”. Methods: The dried r...
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Chromatographic separation of the n-hexane extract of the aerial part of Plectranthus barbatus led to the isolation of five abietane-type diterpenes: dehydroabietane (1); 5,6-didehydro-7-hydroxy-taxodone (2); taxodione (3); 20-deoxocarnosol (4) and 6α,11,12,-trihydroxy-7β,20-epoxy-8,11,13-abietatriene (5). The structures were determined using spectroscopic methods including one- and two-dimensi...
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Three new abietane-type diterpenoids, named callicapoic acid M3 (1), callicapoic acid M4 (2) and callicapoic acid M5 (3), were isolated from the Callicarpa macrophylla Vahl. Their structures were established by spectroscopic techniques (IR, UV, MS, 1D and 2D NMR). All the isolated three compounds were evaluated for inhibitory activity on NO production in LPS-activated RAW 264.7 macrophage cells...
متن کاملAntimicrobial abietane diterpenoids against resistant bacteria and biofilms
Antimicrobial resistance (AMR) is a growing worldwide threat to public health due to the increase of resistant pathogens to the existing antimicrobial therapy. Common and nosocomial infections are beginning to require 2nd and 3rd line antibiotic therapy, increasing time and cost of treatment, and also contributing to the development of multidrug resistance (MDR). Natural products remain an impo...
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ژورنال
عنوان ژورنال: Molecules
سال: 2017
ISSN: 1420-3049
DOI: 10.3390/molecules22111919